Clemastine fumarate

Cat No. 1453

Clemastine fumarate C21H26ClNO.C4H4O4 [14976-57-9]

Price and Availability

Qty
100 mg / $66 In stock
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Chemical Name: (2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy]ethyl]-1-methyl- 2-pyrrolidine fumarate

Biological Activity

H1-receptor antagonist. Clinically-used antihistamine.

Technical Data

M.Wt:
459.97
Formula:
C21H26ClNO.C4H4O4
Solubility:
Soluble to 5 mM in Water
Purity:
>98 %
Storage:
Store at RT
CAS No:
[14976-57-9]

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

Hartmann et al (1981) Modulation of histamine-induced bronchoconstriction with inhaled, oral, and intravenous clemastine in normal and asthmatic subjects. Thorax 36 737. Dorsch et al (1982) Histamine1-histamine2 antagonism: effect of combined clemastine and cimetidine pretreatment on allergen and histamine-induced reactions of the guinea pig lung in vivo and in vitro. Agents Actions 12 113. Nair and Schwartz (1983) Effect of histamine and histamine antagonists on natural and antibody-dependent cellular cytotoxicity of human lymphocytes in vitro. Cell.Immunol. 81 45.

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Keywords: Clemastine fumarate, H1, histamine

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