Pharmacology
All Targets
7-TM Receptors
Ion Channels
Nuclear Receptors
Enzyme-Linked Receptors
Transporters
Enzymes
Other Pharmacology
Cellular Processes
Angiogenesis
Apoptosis
Cell Cycle
Cell Metabolism
Cytoskeleton & Motor Proteins
ECM & Adhesion Molecules
Signal Transduction
Product Type
New Products
Small Molecules
Peptides
Antibodies
Controlled Substances
Toxins
Caged Compounds
Fluorescent Probes
Screening Libraries
Ligand Sets
Other Product Types
Research Area
Cancer
Cardiovascular Disease
Endocrinology
Metabolic Disease
Neuroscience
Pain & Inflammation
Respiratory Disease
Home »
Pharmacology » 7-TM Receptors » Histamine Receptors » Histamine H1 Receptors » Clemastine fumarate
Clemastine fumarate
Cat No. 1453
Price and Availability
Chemical Name: (2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy]ethyl]-1-methyl- 2-pyrrolidine fumarate
Biological Activity
H1-receptor antagonist. Clinically-used antihistamine.Technical Data
M.Wt:459.97
Formula:C21H26ClNO.C4H4O4
Solubility:Soluble to 5 mM in Water
Purity: >98 %
Storage:Store at RT
CAS No:[14976-57-9]
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
Hartmann et al (1981) Modulation of histamine-induced bronchoconstriction with inhaled, oral, and intravenous clemastine in normal and asthmatic subjects. Thorax 36 737. Dorsch et al (1982) Histamine1-histamine2 antagonism: effect of combined clemastine and cimetidine pretreatment on allergen and histamine-induced reactions of the guinea pig lung in vivo and in vitro. Agents Actions 12 113. Nair and Schwartz (1983) Effect of histamine and histamine antagonists on natural and antibody-dependent cellular cytotoxicity of human lymphocytes in vitro. Cell.Immunol. 81 45.Keywords: Clemastine fumarate, H1, histamine
Quick Order
Enter catalog numbers
New Products in this Area
Histamine dihydrochloride
Endogenous histamine receptor agonist
AstemizoleOrally active, potent H1 antagonist. Also hERG K+ channel blocker.
Sign-up for new product e-alerts
Careers at Tocris
Tocris Bioscience currently has an opportunity for an Analytical Chemist and a Senior Synthetic Peptide Chemist.
If you would like to be considered for any positions not currently advertised, we welcome your speculative application.



