New Products

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the new products can be identified by this symbol symbol.

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Cat.No.
Product Name / Activity
Added
5520Echinomycin

Highly potent and selective HIF-1α inhibitor

Jun 2015
5500Protease Inhibitor Cocktail I

Protease inhibitor cocktail for mammalian cells

Jun 2015
5339PFK 15

Selective PFKFB3 inhibitor

Jun 2015
5406ONO 8130

EP1 receptor antagonist

Jun 2015
5336BRD 7116

Inhibitor of leukemia stem cell activity

Jun 2015
5584Aripiprazole

High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist

Jun 2015
5573Chlorphentermine hydrochloride

Serotonin transporter substrate; appetite suppressant

Jun 2015
5355TC-G 1008

Potent and selective GPR39 agonist

Jun 2015
4786PD 0332991 isethionate

Potent, selective Cdk4/6 inhibitor; brain penetrant

Jun 2015
4368Crizotinib

Potent c-MET/ALK inhibitor

Jun 2015
4268Ro 1138452 hydrochloride

Selective prostacyclin IP receptor antagonist

Jun 2015
5547MK6-83

TRPML channel activator

Jun 2015
55145-Aminolevulinic acid hydrochloride

Substrate for detection of δ-aminolevulinic acid dehydratase

Jun 2015
55015-Fluoroorotic acid

Selection reagent for OMP decarboxylase mutants

Jun 2015
5424Deltarasin

High affinity PDEδ-KRAS interaction inhibitor

Jun 2015
5340NSC 617145

Werner syndrome helicase (WRN) helicase inhibitor

Jun 2015
4773ESI 09

EPAC inhibitor

Jun 2015
5564PBS, 100 Tablets

PBS Tablets

Jun 2015
5519(-)-Pentazocine

κ-opioid agonist; antinociceptive

May 2015
5515NADPH reduced form tetrasodium salt

Cofactor for many anabolic enzymes

May 2015
5510X-Gal

Used in cloning procedures with IPTG

May 2015
5509IPTG

Used in cloning procedures with X-GAL

May 2015
5508MOPS

Widely used buffering agent

May 2015
5506Vancomycin HCl

Antibiotic

May 2015
5504D-(+)-Glucose

Naturally occurring monosaccharide

May 2015
5503Ampicillin sodium salt

Antibiotic; selection reagent

May 2015
5502Blasticidin S HCl

Antibiotic; selection reagent for bis, bsr and BSD transformed cells

May 2015
5487DPC AJ1951

Potent parathyroid hormone (PTH) receptor agonist

May 2015
5480KRIBB11

HSF1 inhibitor

May 2015
5414CU-T12-9

Potent TLR1/2 agonist

May 2015
5411RBC8

RalA and RalB GTPase inhibitor

May 2015
5410TC-I 2014

Potent TRPM8 antagonist

May 2015
5304FICZ

High affinity aryl hydrogen receptor (AhR) agonist

May 2015
5293NK 252

Nrf2 activator

May 2015
5267OICR 9429

High affinity and selective WDR5 antagonist

May 2015
5178ASP 7663

Selective TRPA1 activator

May 2015
4957ML 179

Selective liver receptor homolog 1 (LRH1) inverse agonist

May 2015
4809DSR 6434

Potent TLR7 agonist

May 2015
5560Obestatin (human)

Endogenous reported anorexigenic peptide

May 2015
5493XL 413 hydrochloride

Potent and selective Cdc7 inhibitor

May 2015
5382C16

PKR inhibitor

May 2015
5361GSK LSD 1 dihydrochloride

Potent and selective LSD1 inhibitor

May 2015
5543Ropinirole - d7

Deuterated ropinirole (Cat. No. 3680)

May 2015
5542Olanzapine - d8

Deuterated olanzapine (Cat. No. 4349)

May 2015
5541Topiramate - d12

Deuterated topiramate (Cat. No. 3620)

May 2015
5540Acamprosate - d6 calcium

Deuterated acamprosate (Cat. No. 3618)

May 2015
5539Miglustat - d9 hydrochloride

Deuterated miglustat (Cat. No. 3117)

May 2015
5538Risperidone - d4

Deuterated risperidone (Cat. No. 2865)

May 2015
5537Tetrabenazine - d7

Deuterated tetrabenazine (Cat. No. 2175)

May 2015
5536Simvastatin - d6

Deuterated simvastatin (Cat. No. 1965)

May 2015
5535Flupirtine - d4 hydrochloride

Deuterated flupirtine (Cat. No. 2867)

May 2015
5534Citalopram - d4 hydrobromide

Deuterated citalopram (Cat. No. 1427)

May 2015
5533Metformin - d6 hydrochloride

Deuterated metformin (Cat. No. 2864)

May 2015
5532Allopregnanolone - d5

Deuterated allopregnanolone (Cat. No. 3653)

May 2015
5531Memantine - d6 hydrochloride

Deuterated memantine (Cat. No. 0773)

May 2015
5530Clozapine - d8

Deuterated clozapine (Cat. No. 0444)

May 2015
5529Levetiracetam - d6

Deuterated levetiracetam (Cat. No. 2839)

May 2015
5528β-Estradiol - d3

Deuterated β-estradiol (Cat. No. 2824)

May 2015
5527Tomoxetine - d3 hydrochloride

Deuterated tomoxetine (Cat. No. 2011)

May 2015
5526Fluoxetine - d5 hydrochloride

Deuterated fluoxetine (Cat. No. 0927)

May 2015
5525Fenretinide - d4

Deuterated fenretinide (Cat. No. 1396)

May 2015
5524Rp-8-pCPT-cGMPS sodium

PKG inhibitor

May 2015
5473PMX 53

Potent C5a receptor antagonist

May 2015
5393ERK5-IN-1

Potent and selective ERK5 inhibitor

May 2015
5259WWL 113

Ces3 and Ces1f inhibitor

May 2015
5088TC-S 7004

Potent and selective DYRK1A/B inhibitor

May 2015
5544Donepezil - d5 hydrochloride

Deuterated donepezil (Cat. No. 4385)

May 2015
5013AC 710

Potent and selective PDGFR family inhibitor

May 2015
4564JTV 519 fumarate

Ryanodine receptor (RyR) inhibitor

May 2015
5461Foxy 5

Wnt5a peptide mimetic

May 2015
5457SirReal 2

Selective inhibitor of SIRT2

May 2015
5391SPP 86

Potent RET inhibitor

May 2015
5364Hydroxy Dynasore

Dynamin inhibitor; analog of dynasore (Cat. No. 2897)

May 2015
5363NHI 2

LDHA inhibitor

May 2015
5338PK-THPP

Potent TASK-3 channel blocker

May 2015
5330AEG 40730 dihydrochloride

IAP antagonist

May 2015
5204TC-E 5007

Irreversible and selective dipeptidyl peptidase 8 and 9 (DPP-8/9) inhibitor

May 2015
4775SD 2590 hydrochloride

Potent MMP inhibitor

Apr 2015
5087TC NTR1 17

Selective non-peptide NTS1 agonist

Apr 2015
5176JNJ 27141491

Potent and selective human CCR2 antagonist

Apr 2015
5291SIS3

Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Apr 2015
5127P1

Protein disulfide isomerase (PDI) inhibitor

Apr 2015
5328TY 52156

S1P3 receptor antagonist

Apr 2015
5332SP 141

High affinity MDM2 inhibitor

Apr 2015
5320CORM 3

Water-soluble carbon monoxide-releasing molecule

Apr 2015
5479CRID3 sodium salt

Glutathione S-transferase omega 1 (GSTO1) inhibitor

Apr 2015
5474Cytochalasin B

Inhibitor of actin polymerization

Apr 2015
5307MM 102

WDR5/MLL interaction inhibitor

Apr 2015
5460968

Allosteric inhibitor of glutaminase

Apr 2015
5403TAK 960 hydrochloride

Potent and selective PLK1 inhibitor

Apr 2015
5388RQ 00203078

Potent and selective TRPM8 antagonist; orally active

Apr 2015
5356SGX 523

Selective and potent c-MET kinase inhibitor

Apr 2015
5057UNC 2327

Allosteric inhibitor of PRMT3

Apr 2015
5449Erastin

Mitochondria VDAC modulator; also Ferroptosis activator

Apr 2015
5053AC 186

Potent and selective ERβ agonist; neuroprotective

Apr 2015
5043FFN 206 dihydrochloride

Fluorescent VMAT2 substrate

Apr 2015
5513Isotretinoin

Endogenous agonist for retinoic acid receptors; inducer of neuronal differentiation

Apr 2015
5491Aliskiren hemifumarate

Potent renin inhibitor; antihypertensive

Apr 2015
5408Ispinesib

High affinity and selective allosteric KSP inhibitor

Apr 2015
5387ML 354

Selective PAR4 antagonist

Apr 2015
5303GSK 2194069

Potent human fatty acid synthase (hFAS) inhibitor

Apr 2015
5202Furamidine dihydrochloride

Selective PRMT1 inhibitor

Apr 2015
5192NBI 31772

High affinity insulin-like growth factor-I binding protein IGFBP inhibitor

Apr 2015
4737CDDO Im

Nrf2 signaling activator

Apr 2015
5469BDY 650-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5468BDY 630-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5467BDY TR-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5466BDY TMR-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5465BDY FL, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5442Sulforhodamine 101 acid chloride

Fluorescent reagent for the labeling of amines

Mar 2015
5440FITC

Fluorescent reagent for the labeling of amines

Mar 2015
5417BMH 21

RNA polymerase 1 inhibitor; also p53 pathway activator

Mar 2015
5375BIX

BiP (HSP70-5) ER chaperone inducer

Mar 2015
4723T2AA

PCNA inhibitor

Mar 2015
3704APcK 110

KIT inhibitor

Mar 2015
5454BRD 9876

ATP non-competitive kinesin Eg5 inhibitor

Mar 2015
5389Ro 48-8071 fumarate

2,3-Oxidosqualene cyclase (OSC) inhibitor

Mar 2015
5316Elinogrel

P2Y12 antagonist

Mar 2015
5252Ractopamine hydrochloride

Trace amine 1 (TA1) receptor agonist

Mar 2015
5003Rhosin hydrochloride

Rho GTPase inhibitor

Mar 2015
4699SEN 1269

Amyloid-β aggregation inhibitor

Mar 2015
5450XY1

Negative control of SGC 707 (Cat. No. 5367)

Mar 2015
5116PACMA 31

Irreversible protein disulfide isomerase (PDI) inhibitor

Mar 2015
5421BTC

Selective estrogen receptor modulator (SERM)

Mar 2015
5369Norleual

Highly potent HGF/c-MET inhibitor; also AT4 antagonist

Mar 2015
5200FFN 102 mesylate

Selective fluorescent substrate of DAT and VMAT2

Mar 2015
5097A12B4C3

Potent and selective polynucleotide kinase/phosphatase (PKNP) inhibitor

Mar 2015
4806BMS 345541

Selective allosteric inhibitor of IKK; anti-inflammatory

Mar 2015
4669GW 438014A

NPY Y5 receptor antagonist

Mar 2015
5433Heclin

HECT E3 ubiquitin ligase inhibitor

Mar 2015
5413WH-4-023

Potent and selective Lck and Src inhibitor; also inhibits SIK

Mar 2015
5367SGC 707

Potent and selective allosteric inhibitor of PRMT3

Mar 2015
5308ASP 2535

Potent and selective GlyT1 inhibitor

Mar 2015
5240TC-S 7006

Potent and selective Tpl2 (Cot; MAP3K8) inhibitor

Mar 2015
5182OXA 06 dihydrochloride

Potent ROCK inhibitor

Mar 2015
5012PCI 29732

Potent BTK inhibitor

Mar 2015
5432R 7050

Inhibitor of TNF-α receptor 1 signaling

Mar 2015
5380ML 297

Selective Kir3.1/3.2 (GIRK1/2) channel activator

Mar 2015
5305Verteporfin

YAP inhibitor; disrupts YAP-TEAD interactions

Mar 2015
5142Mps1-IN-1 dihydrochloride

Selective monopolar spindle 1 (Mps1) kinase inhibitor

Mar 2015
4574ARN 272

FAAH-like anandamide transporter (FLAT) inhibitor

Mar 2015
5428MRS 5698

High affinity and selective A3 adenosine receptor agonist

Feb 2015
5427D-Luciferin sodium salt

Firefly luciferase substrate

Feb 2015
5425TGN 020

Aquaporin 4 (AQP4) channel blocker

Feb 2015
5420Benzbromarone

TMEM16A/B calcium-activated chloride channel (CaCC) blocker

Feb 2015
5397A01

High affinity Smurf1 inhibitor; enhances BMP signaling

Feb 2015
5358Cariporide

Selective NHE1 inhibitor; cardioprotective and antitumor

Feb 2015
5329CKI 7 dihydrochloride

CK1 inhibitor

Feb 2015
5324M8 B hydrochloride

Potent and selective TRPM8 channel blocker

Feb 2015
5319ACT 462206

Potent, dual orexin receptor antagonist

Feb 2015
5318AEE 788

Potent EGFR and VEGFR inhibitor

Feb 2015
5288R 268712

Potent and selective inhibitor of TGF-βRI

Feb 2015
5149CX 614

AMPAkine; positive allosteric modulator of AMPA

Feb 2015
5412TC AQP1 1

Aquaporin 1 (AQP1) channel blocker

Feb 2015
5344ML 349

Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor

Feb 2015
5153ML 240

ATP-competitive inhibitor of p97 ATPase

Feb 2015
5422XL 184

Potent VEGFR inhibitor; also inhibits other RTKs

Feb 2015
5385GSK 5959

Potent and selective BRPF1 inhibitor

Feb 2015
5353Gap19

Cx43 hemichannel blocker

Feb 2015
5299JNJ 47965567

Potent and selective P2X7 antagonist; brain penetrant

Feb 2015
5279IWP 12

Potent PORCN inhibitor; active in vivo

Feb 2015
5243TC-S 7009

High affinity and selective HIF-2α inhibitor

Feb 2015
5052TG 4-155

High affinity and selective EP2 receptor antagonist

Feb 2015
4837AZD 3988

Potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor

Feb 2015
4624TC-FPR 43

Potent FPR2 agonist

Feb 2015
42344BP-TQS

Allosteric agonist at α7 nAChR

Feb 2015
5399BTB1

Selective and ATP-competitive Kif18A inhibitor

Feb 2015
5376Pregnenolone sulfate sodium salt

NMDA Potentiator

Feb 2015
5371Clemizole hydrochloride

TRPC5 blocker; also H1 antagonist

Feb 2015
5323WDR5 0103

WDR5 antagonist

Feb 2015
5269T 5601640

Selective LIMK2 inhibitor; antitumor

Feb 2015
5214IWP 4

Potent inhibitor of Wnt/β-catenin signaling

Feb 2015
5206JJKK 048

Potent and selective MAGL inhibitor

Feb 2015
51213PO

PFKFB3 inhibitor; antiangiogenic

Feb 2015
5017A 85380 dihydrochloride

High affinity and selective α4β2 agonist

Feb 2015
4905UNC 2400

Negative control of UNC 1999 (Cat. No. 4904)

Feb 2015
5273Bengamide B

Potent inhibitor of NF-κB activation

Jan 2015
5131NAB 2

Protects against α-synuclein toxicity; promotes Rsp5/Nedd4-dependent endosomal transport

Jan 2015
4941PKI 166 hydrochloride

Potent EGFR-kinase inhibitor

Jan 2015
4793CE3F4

Uncompetitive Epac1 inhibitor

Jan 2015
5374GLP-1 (7-37)

Endogenous bioactive GLP-1 receptor ligand

Jan 2015
5373C34

TLR4 inhibitor

Jan 2015
5337ML 365

Potent and selective TASK-1 channel blocker

Jan 2015
5326CHR 6494 trifluoroacetate

Potent and selective haspin kinase inhibitor

Jan 2015
5321PSNCBAM-1

CB1 receptor negative allosteric modulator

Jan 2015
5271UNC 3230

Potent and selective PIP5K1C inhibitor; antinociceptive

Jan 2015
5000FTIDC

Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonist

Jan 2015
4943Sulfidefluor 7 AM

H2S fluorescent probe

Jan 2015
4904UNC 1999

Potent and selective EZH2/EZH1 inhibitor

Jan 2015
4827Garcinol

PCAF/p300 inhibitor; anticancer

Jan 2015
5400(S)-PFI 2 hydrochloride

Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)

Jan 2015
5384TA 02

Induces cardiomyocyte differentiation from hESCs

Jan 2015
5383TA 01

Induces cardiomyocyte differentiation from hESCs

Jan 2015
5345ML 348

Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor

Jan 2015
5331CPI 203

BET bromodomain inhibitor; arrests cell cycle at G1 phase

Jan 2015
5284trans-ISRIB

Integrated stress response (ISR) inhibitor

Jan 2015
5197Spautin 1

USP10 and USP13 inhibitor; inhibits autophagy

Jan 2015
5108TFC 007

Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

Jan 2015
5080TC-G 1003

High affinity somatostatin sst2 receptor agonist

Jan 2015
5009BMS 509744

Potent and selective ITK inhibitor

Jan 2015
4695Ischemin sodium salt

CBP inhibitor; cell permeable

Jan 2015

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Bio-Techne Events

EMBO 2015

The 6th EMBO Meeting 2015

September 5 - 8, 2015

Birmingham, UK