R&D Systems Inc. Tocris Bioscience Boston Biochem

New Products

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the new products can be identified by this symbol symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat.No.
Product Name / Activity
Added
5460968

Allosteric inhibitor of glutaminase

Apr 2015
5403TAK 960 hydrochloride

Potent and selective PLK1 inhibitor

Apr 2015
5388RQ 00203078

Potent and selective TRPM8 antagonist; orally active

Apr 2015
5356SGX 523

Selective and potent c-MET kinase inhibitor

Apr 2015
5057UNC 2327

Allosteric inhibitor of PRMT3

Apr 2015
5449Erastin

Mitochondria VDAC modulator; also Ferroptosis activator

Apr 2015
5053AC 186

Potent and selective ERβ agonist; neuroprotective

Apr 2015
5043FFN 206 dihydrochloride

Fluorescent VMAT2 substrate

Apr 2015
5513Isotretinoin

Endogenous agonist for retinoic acid receptors; inducer of neuronal differentiation

Apr 2015
5491Aliskiren hemifumarate

Potent renin inhibitor; antihypertensive

Apr 2015
5408Ispinesib

High affinity and selective allosteric KSP inhibitor

Apr 2015
5387ML 354

Selective PAR4 antagonist

Apr 2015
5303GSK 2194069

Potent human fatty acid synthase (hFAS) inhibitor

Apr 2015
5202Furamidine dihydrochloride

Selective PRMT1 inhibitor

Apr 2015
5192NBI 31772

High affinity insulin-like growth factor-I binding protein IGFBP inhibitor

Apr 2015
4737CDDO Im

Nrf2 signaling activator

Apr 2015
5469BDY 650-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5468BDY 630-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5467BDY TR-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5466BDY TMR-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5465BDY FL, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5442Sulforhodamine 101 acid chloride

Fluorescent reagent for the labeling of amines

Mar 2015
5440FITC

Fluorescent reagent for the labeling of amines

Mar 2015
5417BMH 21

RNA polymerase 1 inhibitor; also p53 pathway activator

Mar 2015
5375BIX

BiP (HSP70-5) ER chaperone inducer

Mar 2015
4723T2AA

PCNA inhibitor

Mar 2015
3704APcK 110

KIT inhibitor

Mar 2015
5454BRD 9876

ATP non-competitive kinesin Eg5 inhibitor

Mar 2015
5389Ro 48-8071 fumarate

2,3-Oxidosqualene cyclase (OSC) inhibitor

Mar 2015
5316Elinogrel

P2Y12 inhibitor

Mar 2015
5252Ractopamine hydrochloride

Trace amine 1 (TA1) receptor agonist

Mar 2015
5003Rhosin hydrochloride

Rho GTPase inhibitor

Mar 2015
4699SEN 1269

Amyloid-β aggregation inhibitor

Mar 2015
5450XY1

Negative control of SGC 707 (Cat. No. 5367)

Mar 2015
5116PACMA 31

Irreversible protein disulfide isomerase (PDI) inhibitor

Mar 2015
5421BTC

Selective estrogen receptor modulator (SERM)

Mar 2015
5369Norleual

Highly potent HGF/c-MET inhibitor; also AT4 antagonist

Mar 2015
5200FFN 102 mesylate

Selective fluorescent substrate of DAT and VMAT2

Mar 2015
5097A12B4C3

Potent and selective polynucleotide kinase/phosphatase (PKNP) inhibitor

Mar 2015
4806BMS 345541

Selective allosteric inhibitor of IKK; anti-inflammatory

Mar 2015
4669GW 438014A

NPY Y5 receptor antagonist

Mar 2015
5433Heclin

HECT E3 ubiquitin ligase inhibitor

Mar 2015
5413WH-4-023

Potent and selective Lck and Src inhibitor; also inhibits SIK

Mar 2015
5367SGC 707

Potent and selective allosteric inhibitor of PRMT3

Mar 2015
5308ASP 2535

Potent and selective GlyT1 inhibitor

Mar 2015
5240TC-S 7006

Potent and selective Tpl2 (Cot; MAP3K8) inhibitor

Mar 2015
5182OXA 06 dihydrochloride

Potent ROCK inhibitor

Mar 2015
5012PCI 29732

Potent BTK inhibitor

Mar 2015
5432R 7050

Inhibitor of TNF-α receptor 1 signaling

Mar 2015
5380ML 297

Selective Kir3.1/3.2 (GIRK1/2) channel activator

Mar 2015
5305Verteporfin

YAP inhibitor; disrupts YAP-TEAD interactions

Mar 2015
5142Mps1-IN-1 dihydrochloride

Selective monopolar spindle 1 (Mps1) kinase inhibitor

Mar 2015
4574ARN 272

FAAH-like anandamide transporter (FLAT) inhibitor

Mar 2015
5428MRS 5698

High affinity and selective A3 adenosine receptor agonist

Feb 2015
5427D-Luciferin sodium salt

Firefly luciferase substrate

Feb 2015
5425TGN 020

Aquaporin 4 (AQP4) channel blocker

Feb 2015
5420Benzbromarone

TMEM16A/B calcium-activated chloride channel (CaCC) blocker

Feb 2015
5397A01

High affinity Smurf1 inhibitor; enhances BMP signaling

Feb 2015
5358Cariporide

Selective NHE1 inhibitor; cardioprotective and antitumor

Feb 2015
5329CKI 7 dihydrochloride

CK1 inhibitor

Feb 2015
5324M8 B hydrochloride

Potent and selective TRPM8 channel blocker

Feb 2015
5319ACT 462206

Potent, dual orexin receptor antagonist

Feb 2015
5318AEE 788

Potent EGFR and VEGFR inhibitor

Feb 2015
5288R 268712

Potent and selective inhibitor of TGF-βRI

Feb 2015
5149CX 614

AMPAkine; positive allosteric modulator of AMPA

Feb 2015
5412TC AQP1 1

Aquaporin 1 (AQP1) channel blocker

Feb 2015
5344ML 349

Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor

Feb 2015
5153ML 240

ATP-competitive inhibitor of p97 ATPase

Feb 2015
5422XL 184

Potent VEGFR inhibitor; also inhibits other RTKs

Feb 2015
5385GSK 5959

Potent and selective BRPF1 inhibitor

Feb 2015
5353Gap19

Cx43 hemichannel blocker

Feb 2015
5299JNJ 47965567

Potent and selective P2X7 antagonist; brain penetrant

Feb 2015
5279IWP 12

Potent PORCN inhibitor; active in vivo

Feb 2015
5243TC-S 7009

High affinity and selective HIF-2α inhibitor

Feb 2015
5052TG 4-155

High affinity and selective EP2 receptor antagonist

Feb 2015
4837AZD 3988

Potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor

Feb 2015
4624TC-FPR 43

Potent FPR2 agonist

Feb 2015
42344BP-TQS

Allosteric agonist at α7 nAChR

Feb 2015
5399BTB1

Selective and ATP-competitive Kif18A inhibitor

Feb 2015
5376Pregnenolone sulfate sodium salt

NMDA Potentiator

Feb 2015
5371Clemizole hydrochloride

TRPC5 blocker; also H1 antagonist

Feb 2015
5323WDR5 0103

WDR5 antagonist

Feb 2015
5269T 5601640

Selective LIMK2 inhibitor; antitumor

Feb 2015
5214IWP 4

Potent inhibitor of Wnt/β-catenin signaling

Feb 2015
5206JJKK 048

Potent and selective monoacylglycerol lipase (MAGL) inhibitor

Feb 2015
51213PO

PFKFB3 inhibitor; antiangiogenic

Feb 2015
5017A 85380 dihydrochloride

High affinity and selective α4β2 agonist

Feb 2015
4905UNC 2400

Negative control of UNC 1999 (Cat. No. 4904)

Feb 2015
5273Bengamide B

Potent inhibitor of NF-κB activation

Jan 2015
5131NAB 2

Protects against α-synuclein toxicity; promotes Rsp5/Nedd4-dependent endosomal transport

Jan 2015
4941PKI 166 hydrochloride

Potent EGFR-kinase inhibitor

Jan 2015
4793CE3F4

Uncompetitive Epac1 inhibitor

Jan 2015
5374GLP-1 (7-37)

Endogenous bioactive GLP-1 receptor ligand

Jan 2015
5373C34

TLR4 inhibitor

Jan 2015
5337ML 365

Potent and selective TASK-1 channel blocker

Jan 2015
5326CHR 6494 trifluoroacetate

Potent and selective haspin kinase inhibitor

Jan 2015
5321PSNCBAM-1

CB1 receptor negative allosteric modulator

Jan 2015
5271UNC 3230

Potent and selective PIP5K1C inhibitor; antinociceptive

Jan 2015
5000FTIDC

Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonist

Jan 2015
4943Sulfidefluor 7 AM

H2S fluorescent probe

Jan 2015
4904UNC 1999

Potent and selective EZH2/EZH1 inhibitor

Jan 2015
4827Garcinol

PCAF/p300 inhibitor; anticancer

Jan 2015
5400(S)-PFI 2 hydrochloride

Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)

Jan 2015
5384TA 02

Induces cardiomyocyte differentiation from hESCs

Jan 2015
5383TA 01

Induces cardiomyocyte differentiation from hESCs

Jan 2015
5345ML 348

Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor

Jan 2015
5331CPI 203

BET bromodomain inhibitor; arrests cell cycle at G1 phase

Jan 2015
5284trans-ISRIB

Integrated stress response (ISR) inhibitor

Jan 2015
5197Spautin 1

USP10 and USP13 inhibitor; inhibits autophagy

Jan 2015
5108TFC 007

Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

Jan 2015
5080TC-G 1003

High affinity somatostatin sst2 receptor agonist

Jan 2015
5009BMS 509744

Potent and selective ITK inhibitor

Jan 2015
4695Ischemin sodium salt

CBP inhibitor; cell permeable

Jan 2015
5390Tobramycin

Aminoglycoside antibiotic

Dec 2014
5359Rifaximin

Pregnane X receptor agonist; antibiotic

Dec 2014
5281AC 5216

Selective TSPO ligand

Dec 2014
5233CCG 1423

Induces intermediate mesoderm differentiation from ESCs; Rho/SRF pathway inhibitor

Dec 2014
5177WZ 4003

Potent and selective NUAK1/2 inhibitor

Dec 2014
5164CVT 10216

Potent and selective ALDH2 inhibitor

Dec 2014
4366SAG

Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway

Dec 2014
3633Adenosine 5'-(α,β-methylene)diphosphate sodium salt

Ecto-5'-nucleotidase/ CD73 inhibitor

Dec 2014
5395Virodhamine trifluoroacetate

TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist

Dec 2014
5314SMBA 1

High affinity and selective activator of Bax

Dec 2014
5058ANAVEX 2-73

Mixed σ1 and muscarinic receptor agonist; exhibits neuroprotective effects

Dec 2014
5011HMR 1556

Potent and selective Iks channel blocker

Dec 2014
5357DC 260126

FFA1 (GPR40) antagonist

Dec 2014
5347Kisspeptin 10 (dog)

Endogenous ligand for canine kisspeptin receptor

Dec 2014
5309SP 100030

NF-κB and AP-1 dual inhibitor

Dec 2014
5297LY 404187

Selective AMPA receptor positive allosteric modulator

Dec 2014
5286TC-S 7010

Potent and selective Aurora kinase A inhibitor

Dec 2014
5209TAK 21d

Potent FAAH inhibitor

Dec 2014
4832AZ 12216052

Positive allosteric modulator at mGlu8

Dec 2014
4719VU 0463271

Potent and selective inhibitor of the neuronal K-Cl cotransporter (KCC2)

Dec 2014
5276NS 19504

Activator of BKCa (KCa1.1) channels

Dec 2014
5348CPI 613

PDH and KGDH inhibitor

Dec 2014
5294Oltipraz

Nrf2 activator

Dec 2014
5242CLP 257

Selective KCC2 K+-Cl- cotransporter activator

Dec 2014
5237Bryostatin 2

Protein kinase C activator

Dec 2014
5236CC4

High affinity and subtype-selective α6β2 and α4β2 partial agonist

Dec 2014
4890AR-C 118925XX

Selective, competitive P2Y2 receptor antagonist

Dec 2014
5335Angiotensin A

Potent endogenous vasoconstrictor peptide - derivative of angiotensin II (Cat. No. 1158)

Nov 2014
5315Rostafuroxin

Antihypertensive agent; Na+/K+ ATPase modulator

Nov 2014
5310ASP 3026

Potent anaplastic lymphoma kinase (ALK) inhibitor

Nov 2014
5285ZLN 024 hydrochloride

Allosteric AMPK activator

Nov 2014
5283HLM 006474

E2F transcription factor inhibitor

Nov 2014
5040SB 706504

p38 MAPK inhibitor

Nov 2014
4518EPPTB

Trace amine 1 (TA1) receptor antagonist/inverse agonist

Nov 2014
5325Rosiglitazone

Potent and selective PPARγ agonist; antidiabetic agent.

Nov 2014
5313LY 315920

Selective secreted phospholipase A2 (sPLA2) inhibitor

Nov 2014
5272MK 0677

High affinity ghrelin receptor agonist

Nov 2014
5266BAZ2-ICR

Selective BAZ2 inhibitor

Nov 2014
4958Eplivanserin hemifumarate

Potent and selective 5-HT2A antagonist

Nov 2014
5289OF 1

Selective BRPF1B and BRPF2 inhibitor

Nov 2014
5261Dimethylenastron

Inhibitor of mitotic motor kinesin Eg5

Nov 2014
5296Urantide

Selective and competitive urotensin II receptor antagonist

Oct 2014
5277CCG 203971

Inhibits the MRTF/SRF gene transcription pathway; antifibrotic agent

Oct 2014
5275LSN 2463359

Potent and selective positive allosteric modulator at mGlu5

Oct 2014
5264Temsirolimus

mTOR inhibitor; antitumor

Oct 2014
5203NIBR 189

Potent and selective EBI2 (GPR183) receptor antagonist

Oct 2014
5188S 07662

Inverse agonist of the constitutive androstane receptor (CAR)

Oct 2014
5112NS 9283

Positive allosteric modulator of α4β2

Oct 2014
5084MN 64

Potent and selective tankyrase inhibitor

Oct 2014

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