R&D Systems Inc. Tocris Bioscience Boston Biochem

New Products

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the new products can be identified by this symbol symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat.No.
Product Name / Activity
Added
5273Bengamide B

Potent inhibitor of NF-κB activation

Jan 2015
5131NAB 2

Protects against α-synuclein toxicity; promotes Rsp5/Nedd4-dependent endosomal transport

Jan 2015
4941PKI 166 hydrochloride

Potent EGFR-kinase inhibitor

Jan 2015
4793CE3F4

Uncompetitive Epac1 inhibitor

Jan 2015
5374GLP-1 (7-37)

Endogenous bioactive GLP-1 receptor ligand

Jan 2015
5373C34

TLR4 inhibitor

Jan 2015
5337ML 365

Potent and selective TASK-1 channel blocker

Jan 2015
5326CHR 6494 trifluoroacetate

Potent and selective haspin kinase inhibitor

Jan 2015
5321PSNCBAM-1

CB1 receptor negative allosteric modulator

Jan 2015
5271UNC 3230

Potent and selective PIP5K1C inhibitor; antinociceptive

Jan 2015
5000FTIDC

Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonist

Jan 2015
4943Sulfidefluor 7 AM

H2S fluorescent probe

Jan 2015
4904UNC 1999

Potent and selective EZH2/EZH1 histone lysine methyltransferase inhibitor

Jan 2015
4827Garcinol

PCAF/p300 HAT inhibitor; anticancer

Jan 2015
5400(S)-PFI 2 hydrochloride

Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)

Jan 2015
5384TA 02

Induces cardiomyocyte differentiation from hESCs

Jan 2015
5383TA 01

Induces cardiomyocyte differentiation from hESCs

Jan 2015
5345ML 348

Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor

Jan 2015
5331CPI 203

BET bromodomain inhibitor; arrests cell cycle at G1 phase

Jan 2015
5284trans-ISRIB

Integrated stress response (ISR) inhibitor

Jan 2015
5197Spautin 1

USP10 and USP13 inhibitor; inhibits autophagy

Jan 2015
5108TFC 007

Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

Jan 2015
5080TC-G 1003

High affinity somatostatin sst2 receptor agonist

Jan 2015
5009BMS 509744

Potent and selective ITK kinase inhibitor

Jan 2015
4695Ischemin sodium salt

CBP bromodomain inhibitor; cell permeable

Jan 2015
5390Tobramycin

Aminoglycoside antibiotic

Dec 2014
5359Rifaximin

Pregnane X receptor agonist; antibiotic

Dec 2014
5281AC 5216

Selective TSPO ligand

Dec 2014
5233CCG 1423

Induces intermediate mesoderm differentiation from ESCs; Rho/SRF pathway inhibitor

Dec 2014
5177WZ 4003

Potent and selective NUAK1/2 inhibitor

Dec 2014
5164CVT 10216

Potent and selective ALDH2 inhibitor

Dec 2014
4366SAG

Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway

Dec 2014
3633Adenosine 5'-(α,β-methylene)diphosphate sodium salt

Ecto-5'-nucleotidase/ CD73 inhibitor

Dec 2014
5395Virodhamine trifluoroacetate

TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist

Dec 2014
5314SMBA 1

High affinity and selective activator of Bax

Dec 2014
5058ANAVEX 2-73

Mixed σ1 and muscarinic receptor agonist; exhibits neuroprotective effects

Dec 2014
5011HMR 1556

Potent and selective Iks channel blocker

Dec 2014
5357DC 260126

FFA1 (GPR40) antagonist

Dec 2014
5347Kisspeptin 10 (dog)

Endogenous ligand for canine kisspeptin receptor

Dec 2014
5309SP 100030

NF-κB and AP-1 dual inhibitor

Dec 2014
5297LY 404187

Selective AMPA receptor positive allosteric modulator

Dec 2014
5286TC-S 7010

Potent and selective Aurora kinase A inhibitor

Dec 2014
5209TAK 21d

Potent FAAH inhibitor

Dec 2014
4832AZ 12216052

Positive allosteric modulator at mGlu8

Dec 2014
4719VU 0463271

Potent and selective inhibitor of the neuronal K-Cl cotransporter (KCC2)

Dec 2014
5276NS 19504

Activator of BKCa (KCa1.1) channels

Dec 2014
5348CPI 613

PDH and KGDH inhibitor

Dec 2014
5294Oltipraz

Nrf2 activator

Dec 2014
5242CLP 257

Selective KCC2 K+-Cl- cotransporter activator

Dec 2014
5237Bryostatin 2

Protein kinase C activator

Dec 2014
5236CC4

High affinity and subtype-selective α6β2 and α4β2 partial agonist

Dec 2014
4890AR-C 118925XX

Selective, competitive P2Y2 receptor antagonist

Dec 2014
5335Angiotensin A

Potent endogenous vasoconstrictor peptide - derivative of angiotensin II (Cat. No. 1158)

Nov 2014
5315Rostafuroxin

Antihypertensive agent; Na+/K+ ATPase modulator

Nov 2014
5310ASP 3026

Potent anaplastic lymphoma kinase (ALK) inhibitor

Nov 2014
5285ZLN 024 hydrochloride

Allosteric AMPK activator

Nov 2014
5283HLM 006474

E2F transcription factor inhibitor

Nov 2014
5040SB 706504

p38 MAPK inhibitor

Nov 2014
4518EPPTB

Trace amine 1 (TA1) receptor antagonist/inverse agonist

Nov 2014
5325Rosiglitazone

Potent and selective PPARγ agonist; antidiabetic agent.

Nov 2014
5313LY 315920

Selective secreted phospholipase A2 (sPLA2) inhibitor

Nov 2014
5272MK 0677

High affinity ghrelin receptor agonist

Nov 2014
5266BAZ2-ICR

Selective BAZ2 bromodomain inhibitor

Nov 2014
4958Eplivanserin hemifumarate

Potent and selective 5-HT2A antagonist

Nov 2014
5289OF 1

Selective BRPF1B and BRPF2 bromodomain inhibitor

Nov 2014
5261Dimethylenastron

Inhibitor of mitotic motor kinesin Eg5

Nov 2014
5296Urantide

Selective and competitive urotensin II antagonist

Oct 2014
5277CCG 203971

Inhibits the MRTF/SRF gene transcription pathway; antifibrotic agent

Oct 2014
5275LSN 2463359

Potent and selective positive allosteric modulator at mGlu5

Oct 2014
5264Temsirolimus

mTOR inhibitor; antitumor

Oct 2014
5203NIBR 189

Potent and selective EBI2 (GPR183) receptor antagonist

Oct 2014
5188S 07662

Inverse agonist of the constitutive androstane receptor (CAR)

Oct 2014
5112NS 9283

Positive allosteric modulator of α4β2

Oct 2014
5084MN 64

Potent and selective tankyrase inhibitor

Oct 2014
5290KYL

EphA4 receptor tyrosine kinase antagonist; neuroprotective

Oct 2014
5101PD 90780

Inhibits NGF binding to p75NTR

Oct 2014
4701EC 144

High affinity, potent and selective Hsp90 inhibitor

Oct 2014
4691NAV 26

Selective Nav1.7 channel blocker

Oct 2014
3856RuBi-5-HT

RuBi-caged serotonin

Oct 2014
5268Tocriscreen Epigenetics Toolbox

80 Epigenetic modulators supplied pre-dissolved in DMSO (250 μL 10 mM solutions)

Oct 2014
5248XAP 044

Potent and selective mGlu7 antagonist

Oct 2014
5122Dansyl-NECA

Potent and selective fluorescent adenosine A1 agonist

Oct 2014
5046LM11A 31 dihydrochloride

Nonpeptide p75NTR ligand; neuroprotective

Oct 2014
4931EG 00229

Neuropilin 1 (NRP1) receptor antagonist; inhibits VEGFA binding to NRP1

Oct 2014
5089TC-E 5002

Selective histone demethylase KDM2/7 subfamily inhibitor

Oct 2014
4928OXF BD 02

Selective BRD4(1) inhibitor

Oct 2014
4776BIRT 377

Potent negative allosteric modulator of LFA-1

Oct 2014
4724BTT 3033

Selective inhibitor of integrin α2β1

Oct 2014
5280SCH 51344

Potent MTH1 inhibitor

Sep 2014
5215KN 93 phosphate

CaM kinase II inhibitor; water soluble version of KN 93 (Cat. No. 1278).

Sep 2014
5183ETP 45835 dihydrochloride

Mnk1 and Mnk2 inhibitor

Sep 2014
5163A 366

Potent and selective G9a/GLP histone lysine methyltransferase inhibitor

Sep 2014
5140GSK 2830371

Potent and selective allosteric inhibitor of Wip1 phosphatase

Sep 2014
3565ONO AE3 208

High affinity and selective EP4 antagonist

Sep 2014
5238Bryostatin 3

Potent protein kinase C activator

Sep 2014
5189GSK 2837808A

Potent and selective LDHA inhibitor

Sep 2014
5292Cladribine

Deoxyadenosine analog; pro-apoptotic

Sep 2014
5270Toyocamycin

Adenosine analog; antifungal antibiotic

Sep 2014
5258BMS 309403

Potent and selective FABP4 inhibitor

Sep 2014
3591VO-OHpic

Potent PTEN inhibitor

Sep 2014
5207STF 118804

NAMPT inhibitor

Sep 2014
5133GKA 50

Glucokinase activator

Sep 2014
4244TCS 3035

GPR35 agonist

Sep 2014
5263Bazedoxifene acetate

Potent and selective estrogen receptor modulator (SERM)

Sep 2014
5262PF 5274857 hydrochloride

Potent and selective Smoothened (Smo) receptor antagonist

Sep 2014
5251UC 112

IAP and XIAP inhibitor; antitumor

Aug 2014
5235Huwentoxin XVI

Potent and reversible N-type Ca2+ channel blocker

Aug 2014
5155SGI 1027

DNA methyltransferase inhibitor

Aug 2014
4753AL 8697

Potent and selective p38α inhibitor

Aug 2014
4303PPQ 102

Potent, voltage-independent CFTR chloride channel inhibitor

Aug 2014
4161Paricalcitol

Analog of the active form of vitamin D2

Aug 2014
4148Abacavir hemisulfate

Reverse transcriptase inhibitor; antiretroviral

Aug 2014
5257GSK 137647

Potent and selective FFA4 (GPR120) agonist

Aug 2014
5256AH 7614

Selective FFA4 (GPR120) antagonist

Aug 2014
5134MRT 67307 dihydrochloride

Salt inducible kinase (SIK) inhibitor

Aug 2014
4952TRAM 39

Potent KCa3.1 blocker

Aug 2014
4828LDN 209929 dihydrochloride

Potent and selective haspin kinase inhibitor

Aug 2014
5231MPC 6827 hydrochloride

Inhibitor of microtubule polymerization; antimitotic and antitumor

Aug 2014
5196PMX 205

Potent C5a receptor peptide antagonist

Aug 2014
5191PTC 209

Bmi-1 inhibitor; antitumor

Aug 2014
4150Azidothymidine

Selective reverse transcriptase inhibitor; antiretroviral

Aug 2014
3909Toceranib

Potent PDGFR and VEGFR inhibitor

Aug 2014
52556-Bnz-cAMP sodium salt

Cell permeable cAMP analog

Aug 2014
5247NVP ADW 742

ATP-competitive inhibitor of IGF1R

Aug 2014
5186Neuropathiazol

Selective inducer of neuronal differentiation in hippocampal neural progenitors

Aug 2014
5061RKI 1447 dihydrochloride

Potent and selective ROCK inhibitor; antitumor

Aug 2014
4963SC 144 hydrochloride

gp130 inhibitor; blocks cytokine-triggered gp130 signaling

Aug 2014

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New Product Guide

NPG

Highlights 150 new products added in the second half of 2014. View PDF today.

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Bio-Techne Events

DPG 2015

11th Göttingen Meeting of the German Neuroscience Society

March 18 - 21, 2015

Göttingen University, Germany

Booth: 39