New Products

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the new products can be identified by this symbol symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat.No.
Product Name / Activity
Added
5607GNF 7

Ras signaling inhibitor; inhibits Ack1 and GCK

Jul 2015
5601DMXAA

mSTING agonist; induces antitumor immunological responses

Jul 2015
5600BA 1

Potent BRS-3 agonist; also NMBR and GRPR agonist

Jul 2015
5594Spadin

Potent TREK-1 channel inhibitor

Jul 2015
5306KJ Pyr 9

High affinity Myc inhibitor

Jul 2015
4831NS 3861

α3β2 full agonist; also α3β4 partial agonist

Jul 2015
4829ML 239

Breast cancer stem cell inhibitor

Jul 2015
1374SB 215505

5-HT2B/2C antagonist

Jul 2015
5603(-)-JQ1

Inactive control for (+)-JQ1 (Cat. No. 4499)

Jul 2015
5576PFI 4

Potent and selective BRPF1 bromodomain inhibitor

Jul 2015
5443AM 6545

High affinity and selective CB1 antagonist

Jul 2015
5571Lei-Dab 7

Potent, selective KCa2.2 blocker

Jul 2015
5554IHR 1

Potent Smo antagonist

Jul 2015
5489XD 14

BET bromodomain inhibitor

Jul 2015
5485GlyH 101

Reversible, voltage-dependent CFTR chloride channel blocker

Jul 2015
5470QAQ dichloride

Photoswitchable Nav, Kv and Cav channel blocker

Jul 2015
5232AZ 191

Potent DYRK1B inhibitor

Jul 2015
5079ABT 089 dihydrochloride

High affinity and selective α4β2 partial agonist

Jul 2015
4784Edaglitazone

Potent and selective PPARγ agonist; antidiabetic

Jul 2015
5567EPZ 004777

Highly potent DOT1L inhibitor

Jul 2015
5511Sucrose

Disaccharide used in biological buffers

Jul 2015
5507Carbenicillin disodium salt

Antibiotic; selection reagent for AMPR transformed cells

Jul 2015
5505Kanamycin sulfate

Broad spectrum antibiotic

Jul 2015
5498AP 811

High affinity, selective NPR3 antagonist

Jul 2015
5484C 87

TNF-α inhibitor

Jul 2015
5462AAQ chloride

Photoswitchable Kv channel blocker

Jul 2015
5456Zosuquidar trihydrochloride

High affinity P-gp inhibitor

Jul 2015
5379VU 0469650 hydrochloride

Potent and selective negative allosteric modulator of mGlu1

Jul 2015
5378VU 0422288

Selective group III mGlu positive allosteric modulator

Jul 2015
5368Maritoclax

Mcl-1 inhibitor; proapoptotic

Jul 2015
5246MRS 1477

TRPV1 positive allosteric modulator

Jul 2015
5185JTE 607 dihydrochloride

Cytokine release inhibitor; anti-inflammatory

Jul 2015
5129TC-G 1005

Potent and selective TGR5 agonist

Jul 2015
5124PD 404182

High affinity inhibitor of KDO 8-P synthase; also DDAH1 inhibitor

Jul 2015
4860ML 193

Potent, selective GPR55 antagonist

Jul 2015
4702ETP 45658

Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR

Jul 2015
4597NS 8593 hydrochloride

Selective KCa2 (SK) channel negative modulator; inhibits SK currents

Jul 2015
4492Cerestat

Potent and noncompetitive NMDA receptor antagonist

Jul 2015
4482PR 619

Broad spectrum DUB inhibitor

Jul 2015
3105FK 409

NO donor

Jul 2015
5520Echinomycin

Highly potent and selective HIF-1α inhibitor

Jun 2015
5500Protease Inhibitor Cocktail I

Protease inhibitor cocktail for mammalian cells

Jun 2015
5339PFK 15

Selective PFKFB3 inhibitor

Jun 2015
5406ONO 8130

EP1 receptor antagonist

Jun 2015
5336BRD 7116

Inhibitor of leukemia stem cell activity

Jun 2015
5584Aripiprazole

High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist

Jun 2015
5573Chlorphentermine hydrochloride

Serotonin transporter substrate; appetite suppressant

Jun 2015
5355TC-G 1008

Potent and selective GPR39 agonist

Jun 2015
4786PD 0332991 isethionate

Potent, selective Cdk4/6 inhibitor; brain penetrant

Jun 2015
4368Crizotinib

Potent c-MET/ALK inhibitor

Jun 2015
4268Ro 1138452 hydrochloride

Selective prostacyclin IP receptor antagonist

Jun 2015
5547MK6-83

TRPML channel activator

Jun 2015
55145-Aminolevulinic acid hydrochloride

Substrate for detection of δ-aminolevulinic acid dehydratase

Jun 2015
55015-Fluoroorotic acid

Selection reagent for OMP decarboxylase mutants

Jun 2015
5424Deltarasin

High affinity PDEδ-KRAS interaction inhibitor

Jun 2015
5340NSC 617145

Werner syndrome helicase (WRN) helicase inhibitor

Jun 2015
4773ESI 09

EPAC inhibitor

Jun 2015
5564PBS, 100 Tablets

PBS Tablets

Jun 2015
5519(-)-Pentazocine

κ agonist; antinociceptive

May 2015
5515NADPH reduced form tetrasodium salt

Cofactor for many anabolic enzymes

May 2015
5510X-Gal

Used in cloning procedures with IPTG

May 2015
5509IPTG

Used in cloning procedures with X-GAL

May 2015
5508MOPS

Widely used buffering agent

May 2015
5506Vancomycin HCl

Antibiotic

May 2015
5504D-(+)-Glucose

Naturally occurring monosaccharide

May 2015
5503Ampicillin sodium salt

Antibiotic; selection reagent

May 2015
5502Blasticidin S HCl

Antibiotic; selection reagent for bis, bsr and BSD transformed cells

May 2015
5487DPC AJ1951

Potent parathyroid hormone (PTH) receptor agonist

May 2015
5480KRIBB11

HSF1 inhibitor

May 2015
5414CU-T12-9

Potent TLR1/2 agonist

May 2015
5411RBC8

RalA and RalB GTPase inhibitor

May 2015
5410TC-I 2014

Potent TRPM8 antagonist

May 2015
5304FICZ

High affinity aryl hydrogen receptor (AhR) agonist

May 2015
5293NK 252

Nrf2 activator

May 2015
5267OICR 9429

High affinity and selective WDR5 antagonist

May 2015
5178ASP 7663

Selective TRPA1 activator

May 2015
4957ML 179

Selective liver receptor homolog 1 (LRH1) inverse agonist

May 2015
4809DSR 6434

Potent TLR7 agonist

May 2015
5560Obestatin (human)

Endogenous reported anorexigenic peptide

May 2015
5493XL 413 hydrochloride

Potent and selective Cdc7 inhibitor

May 2015
5382C16

PKR inhibitor

May 2015
5361GSK LSD 1 dihydrochloride

Potent and selective LSD1 inhibitor

May 2015
5543Ropinirole - d7

Deuterated ropinirole (Cat. No. 3680)

May 2015
5542Olanzapine - d8

Deuterated olanzapine (Cat. No. 4349)

May 2015
5541Topiramate - d12

Deuterated topiramate (Cat. No. 3620)

May 2015
5540Acamprosate - d6 calcium

Deuterated acamprosate (Cat. No. 3618)

May 2015
5539Miglustat - d9 hydrochloride

Deuterated miglustat (Cat. No. 3117)

May 2015
5538Risperidone - d4

Deuterated risperidone (Cat. No. 2865)

May 2015
5537Tetrabenazine - d7

Deuterated tetrabenazine (Cat. No. 2175)

May 2015
5536Simvastatin - d6

Deuterated simvastatin (Cat. No. 1965)

May 2015
5535Flupirtine - d4 hydrochloride

Deuterated flupirtine (Cat. No. 2867)

May 2015
5534Citalopram - d4 hydrobromide

Deuterated citalopram (Cat. No. 1427)

May 2015
5533Metformin - d6 hydrochloride

Deuterated metformin (Cat. No. 2864)

May 2015
5532Allopregnanolone - d5

Deuterated allopregnanolone (Cat. No. 3653)

May 2015
5531Memantine - d6 hydrochloride

Deuterated memantine (Cat. No. 0773)

May 2015
5530Clozapine - d8

Deuterated clozapine (Cat. No. 0444)

May 2015
5529Levetiracetam - d6

Deuterated levetiracetam (Cat. No. 2839)

May 2015
5528β-Estradiol - d3

Deuterated β-estradiol (Cat. No. 2824)

May 2015
5527Tomoxetine - d3 hydrochloride

Deuterated tomoxetine (Cat. No. 2011)

May 2015
5526Fluoxetine - d5 hydrochloride

Deuterated fluoxetine (Cat. No. 0927)

May 2015
5525Fenretinide - d4

Deuterated fenretinide (Cat. No. 1396)

May 2015
5524Rp-8-pCPT-cGMPS sodium

PKG inhibitor

May 2015
5473PMX 53

Potent C5a receptor antagonist

May 2015
5393ERK5-IN-1

Potent and selective ERK5 inhibitor

May 2015
5259WWL 113

Ces3 and Ces1f inhibitor

May 2015
5088TC-S 7004

Potent and selective DYRK1A/B inhibitor

May 2015
5544Donepezil - d5 hydrochloride

Deuterated donepezil (Cat. No. 4385)

May 2015
5013AC 710

Potent and selective PDGFR family inhibitor

May 2015
4564JTV 519 fumarate

Ryanodine receptor (RyR) inhibitor

May 2015
5461Foxy 5

Wnt5a peptide mimetic

May 2015
5457SirReal 2

Selective inhibitor of SIRT2

May 2015
5391SPP 86

Potent RET inhibitor

May 2015
5364Hydroxy Dynasore

Dynamin inhibitor; analog of dynasore (Cat. No. 2897)

May 2015
5363NHI 2

LDHA inhibitor

May 2015
5338PK-THPP

Potent TASK-3 channel blocker

May 2015
5330AEG 40730 dihydrochloride

IAP antagonist

May 2015
5204TC-E 5007

Irreversible and selective dipeptidyl peptidase 8 and 9 (DPP-8/9) inhibitor

May 2015
4775SD 2590 hydrochloride

Potent MMP inhibitor

Apr 2015
5087TC NTR1 17

Selective non-peptide NTS1 agonist

Apr 2015
5176JNJ 27141491

Potent and selective human CCR2 antagonist

Apr 2015
5291SIS3

Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Apr 2015
5127P1

Protein disulfide isomerase (PDI) inhibitor

Apr 2015
5328TY 52156

S1P3 receptor antagonist

Apr 2015
5332SP 141

High affinity MDM2 inhibitor

Apr 2015
5320CORM 3

Water-soluble carbon monoxide-releasing molecule

Apr 2015
5474Cytochalasin B

Inhibitor of actin polymerization

Apr 2015
5307MM 102

WDR5/MLL interaction inhibitor

Apr 2015
5479CRID3 sodium salt

Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production

Apr 2015
5460968

Allosteric inhibitor of glutaminase

Apr 2015
5403TAK 960 hydrochloride

Potent and selective PLK1 inhibitor

Apr 2015
5388RQ 00203078

Potent and selective TRPM8 antagonist; orally active

Apr 2015
5356SGX 523

Selective and potent c-MET kinase inhibitor

Apr 2015
5057UNC 2327

Allosteric inhibitor of PRMT3

Apr 2015
5449Erastin

Mitochondria VDAC modulator; also Ferroptosis activator

Apr 2015
5053AC 186

Potent and selective ERβ agonist; neuroprotective

Apr 2015
5043FFN 206 dihydrochloride

Fluorescent VMAT2 substrate

Apr 2015
5513Isotretinoin

Endogenous agonist for retinoic acid receptors; inducer of neuronal differentiation

Apr 2015
5491Aliskiren hemifumarate

Potent renin inhibitor; antihypertensive

Apr 2015
5408Ispinesib

High affinity and selective allosteric KSP inhibitor

Apr 2015
5387ML 354

Selective PAR4 antagonist

Apr 2015
5303GSK 2194069

Potent human fatty acid synthase (hFAS) inhibitor

Apr 2015
5202Furamidine dihydrochloride

Selective PRMT1 inhibitor

Apr 2015
5192NBI 31772

High affinity insulin-like growth factor-I binding protein IGFBP inhibitor

Apr 2015
4737CDDO Im

Nrf2 signaling activator

Apr 2015
5469BDY 650-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5468BDY 630-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5467BDY TR-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5466BDY TMR-X, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5465BDY FL, SE

Fluorescent reagent for the labeling of amines

Mar 2015
5442Sulforhodamine 101 acid chloride

Fluorescent reagent for the labeling of amines

Mar 2015
5440FITC

Fluorescent reagent for the labeling of amines

Mar 2015
5417BMH 21

RNA polymerase 1 inhibitor; also p53 pathway activator

Mar 2015
5375BIX

BiP (HSP70-5) ER chaperone inducer

Mar 2015
4723T2AA

PCNA inhibitor

Mar 2015
3704APcK 110

KIT inhibitor

Mar 2015
5454BRD 9876

ATP non-competitive kinesin Eg5 inhibitor

Mar 2015
5389Ro 48-8071 fumarate

2,3-Oxidosqualene cyclase (OSC) inhibitor

Mar 2015
5316Elinogrel

P2Y12 antagonist

Mar 2015
5252Ractopamine hydrochloride

Trace amine 1 (TA1) receptor agonist

Mar 2015
5003Rhosin hydrochloride

Rho GTPase inhibitor

Mar 2015
4699SEN 1269

Amyloid-β aggregation inhibitor

Mar 2015
5450XY1

Negative control of SGC 707 (Cat. No. 5367)

Mar 2015
5116PACMA 31

Irreversible protein disulfide isomerase (PDI) inhibitor

Mar 2015
5421BTC

Selective estrogen receptor modulator (SERM)

Mar 2015
5369Norleual

Highly potent HGF/c-MET inhibitor; also AT4 antagonist

Mar 2015
5200FFN 102 mesylate

Selective fluorescent substrate of DAT and VMAT2

Mar 2015
5097A12B4C3

Potent and selective polynucleotide kinase/phosphatase (PKNP) inhibitor

Mar 2015
4806BMS 345541

Selective allosteric inhibitor of IKK; anti-inflammatory

Mar 2015
4669GW 438014A

NPY Y5 receptor antagonist

Mar 2015
5433Heclin

HECT E3 ubiquitin ligase inhibitor

Mar 2015
5413WH-4-023

Potent and selective Lck and Src inhibitor; also inhibits SIK

Mar 2015
5367SGC 707

Potent and selective allosteric inhibitor of PRMT3

Mar 2015
5308ASP 2535

Potent and selective GlyT1 inhibitor

Mar 2015
5240TC-S 7006

Potent and selective Tpl2 (Cot; MAP3K8) inhibitor

Mar 2015
5182OXA 06 dihydrochloride

Potent ROCK inhibitor

Mar 2015
5012PCI 29732

Potent BTK inhibitor

Mar 2015
5432R 7050

Inhibitor of TNF-α receptor 1 signaling

Mar 2015
5380ML 297

Selective Kir3.1/3.2 (GIRK1/2) channel activator

Mar 2015
5305Verteporfin

YAP inhibitor; disrupts YAP-TEAD interactions

Mar 2015
5142Mps1-IN-1 dihydrochloride

Selective monopolar spindle 1 (Mps1) kinase inhibitor

Mar 2015
4574ARN 272

FAAH-like anandamide transporter (FLAT) inhibitor

Mar 2015
5428MRS 5698

High affinity and selective A3 adenosine receptor agonist

Feb 2015
5427D-Luciferin sodium salt

Firefly luciferase substrate

Feb 2015
5425TGN 020

Aquaporin 4 (AQP4) channel blocker

Feb 2015
5420Benzbromarone

TMEM16A/B calcium-activated chloride channel (CaCC) blocker

Feb 2015
5397A01

High affinity Smurf1 inhibitor; enhances BMP signaling

Feb 2015
5358Cariporide

Selective NHE1 inhibitor; cardioprotective and antitumor

Feb 2015
5329CKI 7 dihydrochloride

CK1 inhibitor

Feb 2015
5324M8 B hydrochloride

Potent and selective TRPM8 channel blocker

Feb 2015
5319ACT 462206

Potent, dual orexin receptor antagonist

Feb 2015
5318AEE 788

Potent EGFR and VEGFR inhibitor

Feb 2015
5288R 268712

Potent and selective inhibitor of TGF-βRI

Feb 2015
5149CX 614

AMPAkine; positive allosteric modulator of AMPA

Feb 2015
5412TC AQP1 1

Aquaporin 1 (AQP1) channel blocker

Feb 2015
5344ML 349

Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor

Feb 2015
5153ML 240

ATP-competitive inhibitor of p97 ATPase

Feb 2015
5422XL 184

Potent VEGFR inhibitor; also inhibits other RTKs

Feb 2015
5385GSK 5959

Potent and selective BRPF1 inhibitor

Feb 2015
5353Gap19

Cx43 hemichannel blocker

Feb 2015
5299JNJ 47965567

Potent and selective P2X7 antagonist; brain penetrant

Feb 2015
5279IWP 12

Potent PORCN inhibitor; active in vivo

Feb 2015
5243TC-S 7009

High affinity and selective HIF-2α inhibitor

Feb 2015
5052TG 4-155

High affinity and selective EP2 receptor antagonist

Feb 2015
4837AZD 3988

Potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor

Feb 2015
4624TC-FPR 43

Potent FPR2 agonist

Feb 2015
42344BP-TQS

Allosteric agonist at α7 nAChR

Feb 2015
5399BTB1

Selective and ATP-competitive Kif18A inhibitor

Feb 2015
5376Pregnenolone sulfate sodium salt

NMDA Potentiator

Feb 2015
5371Clemizole hydrochloride

TRPC5 blocker; also H1 antagonist

Feb 2015
5323WDR5 0103

WDR5 antagonist

Feb 2015
5269T 5601640

Selective LIMK2 inhibitor; antitumor

Feb 2015
5214IWP 4

Potent inhibitor of Wnt/β-catenin signaling

Feb 2015
5206JJKK 048

Potent and selective MAGL inhibitor

Feb 2015
51213PO

PFKFB3 inhibitor; antiangiogenic

Feb 2015
5017A 85380 dihydrochloride

High affinity and selective α4β2 agonist

Feb 2015
4905UNC 2400

Negative control of UNC 1999 (Cat. No. 4904)

Feb 2015

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