R&D Systems Inc. Tocris Bioscience Boston Biochem

New Products

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the new products can be identified by this symbol symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat.No.
Product Name / Activity
Added
5254FH 1

Enhances iPSC-derived hepatocyte differentiation and maturation

Jul 2014
5223Monensin sodium salt

Sodium ionophore; antibacterial agent

Jul 2014
5213LL 37

Antimicrobial peptide derivative of human cathelicidin

Jul 2014
5171NBOH-2C-CN hydrochloride

Potent and selective 5-HT2A agonist

Jul 2014
5109SB 743921 hydrochloride

Potent kinesin spindle protein (KSP) inhibitor

Jul 2014
5068ITD 1

Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs

Jul 2014
5250Ramipril

Non-peptide, competitive angiotensin converting enzyme (ACE) inhibitor

Jul 2014
5173MS 436

Potent and selective BRD4 bromodomain inhibitor

Jul 2014
5161ML 154

Potent and selective neuropeptide S receptor (NPSR) antagonist

Jul 2014
4767WAY 316606 hydrochloride

Secreted frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling

Jul 2014
4734TRC 051384

Inducer of heat shock protein Hsp70

Jul 2014
5228Urea

Used to solubilize and denature proteins

Jul 2014
5227Tricine

Electrophoresis buffer

Jul 2014
5226Sodium phosphate monobasic

Commonly used in biological assay buffers

Jul 2014
5225Ponceau S Staining Solution

Stain used to detect protein bands after Western blotting

Jul 2014
5224MTT

Reagent used in the measurement of cell proliferation

Jul 2014
5222Hematoxylin

Dye used to stain cell nuclei

Jul 2014
5221Guanidine Hydrochloride

Protein denaturant

Jul 2014
5220Glycerol

Widely used in sample buffer preparation

Jul 2014
5219L-Glutathione Reduced

Endogenous antioxidant

Jul 2014
5218Bromophenol Blue

Dye used in gel loading buffers

Jul 2014
5217Bovine Serum Albumin

Widely used blocking agent for ELISA and blotting

Jul 2014
5216BIS-TRIS

Commonly used buffering agent

Jul 2014
5095DBM 1285 dihydrochloride

p38 MAPK inhibitor; anti-inflammatory

Jul 2014
4993NSC 624206

Ubiquitin-activating enzyme (E1) inhibitor

Jul 2014
4169KS 176

Selective BCRP inhibitor

Jul 2014
4139Aprotinin

Competitive serine protease inhibitor

Jul 2014
3177Boric acid

Widely used in buffers for electrophoresis

Jul 2014
3166Sodium dodecyl sulphate solution

Detergent used in electrophoresis of proteins

Jul 2014
3165Polyoxyethylenesorbitan monolaurate

Detergent used for protein extraction

Jul 2014
3156Dulbecco's PBS

Buffered saline used in mammalian cell culture

Jul 2014
3153Sodium phosphate dibasic

Commonly used in biological assay buffers

Jul 2014
3150Potassium phosphate monobasic

Commonly used in biological assay buffers

Jul 2014
5245Ebselen

Glutathione peroxidase mimic; peroxynitrite scavenger

Jul 2014
5230BRD 7552

PDX1 transcription factor inducer; increases insulin expression

Jul 2014
5184BDS I

Potent and reversible Kv3.4 potassium channel blocker; neuroprotective

Jul 2014
4745LIMKi 3

Potent LIM kinase inhibitor; antitumor

Jul 2014
4694Ro 5-3335

Core binding factor inhibitor; attenuates hematopoiesis differentiation

Jul 2014
4625TC OT 39

Nonpeptide oxytocin and V2 receptor partial agonist; also a V1a receptor antagonist

Jul 2014
5190FRAX 486

Potent p21-activated kinase (PAK) inhibitor; brain penetrant and orally bioavailable

Jul 2014
5179TCID

Selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor

Jul 2014
5141AZD 5582 dihydrochloride

Dimeric Smac mimetic; potent IAP inhibitor

Jul 2014
50332-MPPA

Selective glutamate carboxypeptidase II (GCP II) inhibitor; orally bioavailable

Jul 2014
4842BIX 02189

Selective MEK5 and ERK5 inhibitor

Jul 2014
4783Lu AA 47070

Prodrug of a potent and selective adenosine A2A receptor antagonist

Jul 2014
4750TC Mps1 12

Potent and selective monopolar spindle 1 (Mps1) kinase inhibitor; orally active

Jul 2014
2472Triacsin C

Inhibitor of acyl-CoA synthetase

Jul 2014
5208E 64

Potent and irreversible cysteine protease inhibitor

Jun 2014
5195Agitoxin 2

Potent Shaker K+ channel blocker

Jun 2014
5181Tolvaptan

Potent and selective vasopressin V2 receptor antagonist; renoprotective and orally active

Jun 2014
5107GSK 2606414

Potent and selective PERK inhibitor; orally bioavailable

Jun 2014
5044SR 3576

Highly potent and selective JNK3 inhibitor

Jun 2014
5198AZ 20

Potent and selective ATR kinase inhibitor; antitumor

Jun 2014
4945ML 347

Potent and selective ALK1 and ALK2 inhibitor

Jun 2014
5199AZD 7762 hydrochloride

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2

Jun 2014
5098KRCA 0008

Potent Ack1 and ALK dual inhibitor; orally bioavailable

Jun 2014
5077DDR1-IN-1 dihydrochloride

Selective DDR1 inhibitor

Jun 2014
4888KHS 101 hydrochloride

Selective inducer of neuronal differentiation

Jun 2014
5086PA 452

RXR antagonist

Jun 2014
5005DR 4485 hydrochloride

High affinity and selective 5-HT7 antagonist; orally bioavailable

Jun 2014
4854ML 00253764 hydrochloride

Melanocortin MC4 receptor antagonist; brain penetrant

Jun 2014
4598PHT 427

Dual Akt and PDK1 inhibitor; antitumor

Jun 2014
5175AEBSF

Broad spectrum, irreversible inhibitor of serine proteases

May 2014
5110GSK 1562590 hydrochloride

High affinity, selective urotensin II (UT) receptor antagonist

May 2014
5051BIO 5192

Highly potent and selective inhibitor of integrin α4β1

May 2014
5021TC-G 1000

Potent and selective α2D agonist

May 2014
5169Noradrenaline bitartrate

Endogenous adrenergic hormone and neurotransmitter

May 2014
5180Ferrostatin 1

Selective inhibitor of erastin induced ferroptosis

May 2014
5151Prosaptide TX14(A)

Potent GPR37 and GPR37L1 agonist

May 2014
5113AbK

Photo-crosslinking probe

May 2014
5036ML 786 dihydrochloride

Potent Raf kinase inhibitor; orally bioavailable

May 2014
4886RU-SKI 43 hydrochloride

Hedgehog acyltransferase (Hhat) inhibitor; cell permeable

May 2014
4875Senexin A

Cyclin-dependent kinase 8 (cdk8) inhibitor

May 2014
2305Tautomycetin

Selective PP1 inhibitor

May 2014
5172FLI 06

Inhibitor of Notch signaling

May 2014
5148Wnt-C59

Highly potent Porcn inhibitor

May 2014
5128C 21

Selective PRMT1 arginine methyltransferase inhibitor

May 2014
4964R 1485 dihydrochloride

Selective and high affinity 5-HT6 antagonist

May 2014
1286LY 231617

Antioxidant; neuroprotective in vitro and in vivo

May 2014
5099TC-E 5003

Selective PRMT1 arginine methyltransferase inhibitor

May 2014
5050CASIN

Cdc42 GTPase inhibitor

May 2014
4978Pyrintegrin

Enhances survival of human ESCs following enzymatic dissociation

May 2014
4934MA 2029

Potent and selective, competitive motilin receptor antagonist; orally active

May 2014
4898TC-E 5006

γ-secretase modulator; reduces Aβ42 levels

May 2014
5135Propidium iodide

Red-fluorescent DNA stain; membrane impermeant to live cells

Apr 2014
5106GSK 2193874

Potent and selective TRPV4 inhibitor; orally active

Apr 2014
5076SZL P1-41

Selective Skp2 inhibitor; suppresses E3 ligase activity

Apr 2014
4893XL 388

Potent and selective mTOR inhibitor; antitumor

Apr 2014
4604PTIQ

Potent MMP-3 expression inhibitor; neuroprotective

Apr 2014
4557GTS 21 dihydrochloride

Partial agonist at α7 nAChR

Apr 2014
5154HNGF6A

Humanin analog; increases insulin sensitivity

Apr 2014
5145AI-3

ARE activator; induces Nrf2-ARE-dependent transcription

Apr 2014
4949MaxiPost

Potassium channel modulator; exerts subtype-specific effects

Apr 2014
5168Rose Bengal

Potent EAAT and VMAT inhibitor; cell permeable

Apr 2014
5111GSK 1838705

Potent and selective IR and IGF1R inhibitor; antitumor

Apr 2014
4826SUN 11602

Basic fibroblast growth factor (bFGF) mimetic; neuroprotective

Apr 2014
5167Congo Red

EAAT inhibitor; also an amyloid fibril-binding dye

Apr 2014
5144CFM 4

CARP-1 mimetic; proapoptotic

Apr 2014
5119Calcein AM

Cell permeable compound; hydrolyzed to become fluorescent in living cells

Apr 2014
4766SIB 1508Y maleate

Potent agonist of α4β2, α2β4, α4β4 and α3β4 nACh receptors

Apr 2014
4569PS 1145 dihydrochloride

Selective IKK inhibitor; orally active

Apr 2014
5132UNC 0642

Potent and selective G9a and GLP histone lysine methyltransferase inhibitor

Apr 2014
5118SynaptoRedTM C2

Fluorescent dye; stains synaptic vesicles

Apr 2014
5072PFI 3

Potent and selective SMARCA4 and polybromo 1 inhibitor; also inhibits SMARCA2

Apr 2014
5065NSC 319726

Reactivator of mutant p53

Apr 2014
5035AS 2034178

Selective FFA1 (GPR40) agonist

Apr 2014
4969LY 2389575 hydrochloride

Selective negative allosteric modulator of mGlu3

Apr 2014
4777ML 277

Selective Kv7.1 (KCNQ1) potassium channel activator; augments IKs current

Apr 2014
4763Pyridostatin pentahydrochloride

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

Apr 2014
4605(±)-SLV 319

Potent and selective CB1 receptor antagonist

Apr 2014
4892(R)-PFI 2 hydrochloride

Potent and selective SETD7 histone lysine methyltransferase inhibitor

Mar 2014
4528(±)-NBI 74330

Potent and selective CXCR3 antagonist

Mar 2014
5138RSVA 405

AMPK activator

Mar 2014
5025Necrosulfonamide

Necroptosis inhibitor

Mar 2014
4924CEP 1347

Inhibitor of JNK signaling

Mar 2014
4643PCI 34051

Potent and selective histone deacetylase 8 (HDAC8) inhibitor; induces apoptosis in T cell-derived cell lines

Mar 2014
4580Atiprimod dihydrochloride

JAK2 inhibitor

Mar 2014
4551Purmorphamine

Smo receptor agonist

Mar 2014
5158Morphine hydrochloride

Narcotic opioid analgesic

Mar 2014
5146Sulforhodamine 101

Fluorescent dye; selective astrocyte marker

Mar 2014
5130CTCE 9908

CXCR4 antagonist; antitumor

Mar 2014
5126iMDK

Potent suppressor of MDK expression; antitumor

Mar 2014
5074ANQ 11125

Selective motilin receptor antagonist

Mar 2014
5041PAOPA

Dopamine D2 receptor allosteric modulator

Mar 2014
4976ML 289

Selective negative allosteric modulator at mGlu3

Mar 2014
4946AIM 100

Potent and selective Ack1 inhibitor

Mar 2014
4899ML 120B dihydrochloride

Novel IKK2-selective inhibitor

Mar 2014
4859ML 202

Pyruvate kinase M2 activator

Mar 2014
4780VUF 11207 fumarate

Potent CXCR7 agonist

Mar 2014
4747TC-G 1006

Potent and selective sphingosine-1-phosphate receptor 1 (S1P1) agonist

Mar 2014
4697A 331440 dihydrochloride

Selective H3 antagonist

Mar 2014
3322ZD 9379

Brain penetrant NMDA antagonist, acts at glycine site

Mar 2014
5160Medetomidine hydrochloride

Potent, highly selective α2 agonist

Mar 2014
5143Ononetin

TRPM3 blocker

Mar 2014
5115OXA (17-33)

Potent and selective peptide OX1 antagonist

Mar 2014
5082LDN 212320

Increases EAAT2 expression; neuroprotective

Mar 2014
4983ACT 335827

Potent and selective OX1 antagonist

Mar 2014
4130KN 92

Inactive analog of KN 93. K+ channel (Kv) blocker

Mar 2014
5157DMNPE-caged ATP diammonium salt

Caged ATP

Feb 2014
5156Ivermectin B1a-d2

Deuterated ivermectin B1a (Cat. No. 1260)

Feb 2014
4977RN 1 dihydrochloride

LSD1 inhibitor

Feb 2014
4908GNF 5

Selective allosteric inhibitor of Bcr-Abl; analog of GNF 2 (Cat. No. 4399)

Feb 2014
4872KML 29

Highly selective and potent monoacylglycerol lipase (MAGL) inhibitor

Feb 2014
4808FK 866 hydrochloride

Non-competitive and potent NAMPT inhibitor; induces apoptosis and autophagy

Feb 2014
4778BETP

Positive allosteric modulator of GLP-1 receptors

Feb 2014
4673SB 674042

Potent and selective non-peptide OX1 antagonist

Feb 2014
5096AdipoRon hydrochloride

Orally active AdipoR1 and AdipoR2 agonist; antidiabetic

Feb 2014
5094PG 931

Potent and selective MC4 receptor agonist

Feb 2014
5085L 012 sodium salt

Chemiluminescent ROS and RNS indicator

Feb 2014
5045L002

p300 inhibitor

Feb 2014
4994PYZD 4409

Ubiquitin-activating enzyme (E1) inhibitor

Feb 2014
4883CU CPT 4a

Selective TLR3 antagonist

Feb 2014
4866ML 190

Selective κ opioid receptor antagonist

Feb 2014
4603LUF 5834

Potent adenosine A2A and A2B receptor partial agonist

Feb 2014
4173MDL 100907

Potent and selective 5-HT2A antagonist

Feb 2014
4078PF 8380

Potent autotaxin inhibitor

Feb 2014
5147Istradefylline

Potent and selective adenosine A2A receptor antagonist

Feb 2014
5139Telmisartan

AT1 antagonist; PPARγ partial agonist

Feb 2014
5136Rizatriptan benzoate

Potent 5-HT1B/1D agonist

Feb 2014
5117Hoechst 33342

Fluorescent DNA stain

Feb 2014
4951SA 4503 dihydrochloride

Selective σ1 receptor agonist

Feb 2014
4622MK 1903

Potent and selective GPR109A (HCA2) agonist

Feb 2014
4550IQ 3

Selective JNK3 inhibitor

Feb 2014
4459TC-S 7005

Potent and selective PLK2 inhibitor

Feb 2014
4288ISO 1

Macrophage migration inhibitory factor (MIF) inhibitor

Feb 2014
3824CD 2314

Selective RARβ agonist

Feb 2014
5092Acridine Orange hydrochloride

Nucleic acid binding dye

Feb 2014
5063SRPIN340

Selective SRPK1 inhibitor

Feb 2014

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