New Products

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the new products can be identified by this symbol symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat.No.
Product Name / Activity
Added
5764Deferoxamine mesylate

Iron chelator; also hypoxia mimetic

Feb 2016
5763(R)-Citalopram oxalate

Enantiomer of escitalopram oxalate

Feb 2016
5752PF 06260933 dihydrochloride

MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK

Feb 2016
5647MI 192

Potent and selective HDAC2/3 inhibitor

Feb 2016
5645IPSU

OX2 receptor antagonist; orally bioavailable

Feb 2016
5739Prostratin

PKC activator; also NF-κB activator

Jan 2016
5735S3QEL 2

Suppressor of Complex III superoxide production

Jan 2016
5734L-Dehydroascorbic acid

GLUT1 substrate; oxidized form of L-Ascorbic acid

Jan 2016
5656DY 268

Potent FXR antagonist

Jan 2016
5642CMPD101

Potent and selective GRK2/3 inhibitor

Jan 2016
5459Cytosporone B

High affinity Nur77 agonist

Jan 2016
5710NFAT inhibitor, Cell Permeable

Cell permeable NFAT inhibitor

Jan 2016
5620BDY FL-X, SE

Fluorescent reagent for the labeling of amines

Jan 2016
2825TBCA

Selective CK2 inhibitor

Jan 2016
5697PMX 53c

Negative control for PMX 53 (Cat. No. 5473)

Dec 2015
5635GSK 2801

Selective BAZ2A and BAZ2B inhibitor

Dec 2015
5583Quin C1

Potent and selective FPR2 agonist

Dec 2015
5418CYM 5520

Selective S1P2 allosteric agonist

Dec 2015
5398NQTrp

Potent inhibitor of Aβ oligomer and fibril formation

Dec 2015
5736Aphidicolin

DNA polymerase α, δ and ε inhibitor

Dec 2015
5641MSC 2032964A

Potent and selective ASK1 inhibitor; orally bioavailable

Dec 2015
5613AZD 9272

Potent and selective mGlu5 antagonist; brain penetrant

Dec 2015
5575IQ 1S

JNK inhibitor; anti-inflammatory

Dec 2015
5495CW 008

PKA signaling activator; promotes osteogenesis from hMSCs

Dec 2015
5377VU 0483605

Positive allosteric modulator at mGlu1

Dec 2015
5037Nepicastat hydrochloride

Potent and selective dopamine β-hydroxylase (DBH) inhibitor; orally bioavailable

Dec 2015
5716PF 06447475

Potent LRRK2 inhibitor; neuroprotective

Dec 2015
57124-ethynyl-N-ethyl-1,8-naphthalimide

Click-activated fluorescent probe

Dec 2015
5684Naloxone 3-glucuronide carbonic acid salt

Naloxone conjugate

Dec 2015
5606LOC14

High affinity protein disulfide isomerase (PDI) modulator

Dec 2015
5549Perlapine

Potent and selective hM3Dq DREADD agonist

Dec 2015
5517AMG PERK 44

Potent and selective PERK inhibitor; orally bioavailable

Dec 2015
5512BIX NHE1 inhibitor

Potent and selective NHE1 inhibitor

Dec 2015
5471CGP 60474

Potent dual cdk1/cdk2 inhibitor

Dec 2015
4845A 939572

SCD1 inhibitor; induces cell death of undifferentiated human ESCs

Dec 2015
5582TAT-cyclo-CLLFVY

Selective HIF-1 dimerization inhibitor

Dec 2015
5559SSR 180711 hydrochloride

Partial agonist at α7 nAChR

Dec 2015
5472CGP 74514 dihydrochloride

Potent cdk1 inhibitor

Dec 2015
5563VTP 27999 trifluoroacetate

Highly potent and selective renin inhibitor

Nov 2015
5552Liothyronine sodium

Thyroid hormone (T3) analog; also promotes adipogenic differentiation of MSCs

Nov 2015
5322VU 0409106

Potent and selective negative allosteric modulator at mGlu5

Nov 2015
5260KG 5

PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor

Nov 2015
5711Nilvadipine

Syk kinase inhibitor; inhibits Aβ production

Nov 2015
5690Centrinone B

High affinity and selective PLK4 inhibitor

Nov 2015
5622HTH 01-015

Potent and selective NUAK1 inhibitor

Nov 2015
5476Cell Activation Cocktail 500X

Cell activation cocktail

Nov 2015
5475Kobe 0065

H-Ras-cRaf1 interaction inhibitor; inhibits Raf signaling

Nov 2015
5446G 28UCM

FASN inhibitor

Nov 2015
5682OSU 03012

PDK1 inhibitor; inhibits Akt signaling

Nov 2015
56981-Methyl-D-tryptophan

Indoleamine 2,3-dioxygenase (IDO) inhibitor

Nov 2015
5676Guangxitoxin 1E

Potent Kv2.1 and Kv2.2 channel blocker

Nov 2015
5605CINPA 1

Potent CAR antagonist

Nov 2015
5653JW 74

Wnt pathway inhibitor

Oct 2015
5633MRS 2905

Potent and selective P2Y14 receptor agonist

Oct 2015
5626SR 7826

Potent and selective LIMK inhibitor; antitumor

Oct 2015
5619N-Acetylcysteine amide

Glutathione (GSH) precursor; neuroprotective

Oct 2015
5562Mps BAY 2a

Potent and selective Mps1 kinase inhibitor

Oct 2015
5455W 54011

High affinity C5a receptor antagonist

Oct 2015
5287NSC 636819

KDM4A/KDM4B inhibitor

Oct 2015
5680Vatalanib succinate

Potent VEGFR inhibitor; also aromatase inhibitor

Oct 2015
5631LDN 193188

Inhibitor of phosphatidylcholine transfer protein (PC-TP)

Oct 2015
5611Salvinorin B

Activates the κ-opioid DREADD (KORD)

Oct 2015
5610DFHBI 1T

Mimic of GFP fluorophore for imaging RNA in living cells

Oct 2015
5609DFHBI

Mimic of GFP fluorophore for imaging RNA in living cells.

Oct 2015
5522Napabucasin

STAT3 inhibitor; blocks cancer stem cell self-renewal

Oct 2015
5210PDP-EA

FAAH activator

Oct 2015
45888MDP

Potent equilibrative nucleoside transporter (ENT) inhibitor

Oct 2015
5548DREADD agonist 21

Potent hM3Dq DREADD agonist

Oct 2015
5342SCR7 pyrazine

Enhances homology-directed repair (HDR) efficiency

Oct 2015
5683MMAE

Potent dolastatin 10 analog; antitumor

Oct 2015
5453GR 125487 - d3 sulfamate

Deuterated GR 125487 (Cat. No. 1658)

Oct 2015
5431SR 13800

Potent MCT1 inhibitor

Oct 2015
4330AMG 21629

Potent and selective TRPV1 antagonist

Oct 2015
5679N-Acetylpurinomycin

Downregulates SnoN and Ski protein expression; promotes TGF-β signaling

Sep 2015
5677RFRP-1 (human)

Potent NPFF receptor agonist

Sep 2015
5636GS 143

β-TrCP1 ligase inhibitor

Sep 2015
5591I-BRD9

Potent and selective BRD9 inhibitor

Sep 2015
5588UF 010

Class I HDAC inhibitor

Sep 2015
5640PF 06463922

High affinity and selective ALK and ROS1 inhibitor

Sep 2015
5553Sephin 1

Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1

Sep 2015
5546NI 57

Potent and selective BRPF bromodomain inhibitor

Sep 2015
5463PA 1 dihydrochloride

Photoswitchable ENaC blocker

Sep 2015
5317WWL 123

α/β-hydrolase domain 6 (ABHD6) inhibitor; antiepileptic

Sep 2015
5229ABP 688

High affinity human mGlu5 receptor antagonist

Sep 2015
5674GW 501516

Potent and selective PPARδ agonist

Sep 2015
5545BX 430

Selective P2X4 allosteric antagonist

Sep 2015
5429NG 25

TGF-β-activated kinase (TAK1) inhibitor

Sep 2015
5349Treprostinil

Potent prostacyclin (PGI2) analog

Sep 2015
3375Dolastatin 10 trifluoroacetate

Tubulin polymerization inhibitor

Sep 2015
561218A

HIV cell entry blocker

Sep 2015
5604MI 14

Potent and selective PI 4-kinase IIIβ inhibitor

Sep 2015
5586Yoda 1

Piezo1 channel activator

Sep 2015
5566DG 172 dihydrochloride

Potent PPARβ/δ inverse agonist; promotes BMC differentiation

Sep 2015
5492BMS 566419

Inosine monophosphatase dehydrogenase (IMPDH) inhibitor

Sep 2015
5648Hydroxychloroquine sulfate

Autophagy inhibitor; also TLR9 inhibitor

Sep 2015
5577S4

High affinity and selective CA IX and CA XII inhibitor

Sep 2015
5568S 18886

Potent thromboxane A2 (TP) antagonist

Sep 2015
5565Tiplaxtinin

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

Sep 2015
4726CTA 056

ITK inhibitor

Sep 2015
5659AmmTX3

KV4 channel blocker

Sep 2015
5617AZD 1480

Potent and selective JAK2 inhibitor; antiangiogenic

Sep 2015
5585Balicatib

Potent and selective cathepsin K inhibitor

Sep 2015
54905J 4

CRAC channel blocker; anti-inflammatory

Sep 2015
5438NTRC 824

Potent and selective non-peptide NTS2 antagonist

Sep 2015
5211AM-TS23

DNA polymerase λ and β inhibitor

Sep 2015
5627HFI 142

Insulin-regulated aminopeptidase (IRAP) inhibitor

Aug 2015
56026877002

CD40-TRAF6 interaction inhibitor

Aug 2015
5589WAY 181187 oxalate

High affinity and selective 5-HT6 agonist

Aug 2015
5580DMH2

Type I BMP receptor inhibitor

Aug 2015
54026bK

Insulin degrading enzyme (IDE) inhibitor

Aug 2015
4961TC-S 7001

Potent and highly selective ROCK inhibitor; orally active

Aug 2015
4926UPF 648

Potent kynurenine 3-monooxygenase (KMO) inhibitor

Aug 2015
5639O4I1

Oct3/4 inducer

Aug 2015
5430AS 2444697

Potent and selective IRAK4 inhibitor

Aug 2015
5629Dolasetron mesylate

Potent and selective 5-HT3 antagonist

Aug 2015
5482TDFA

PAD4 inhibitor

Aug 2015
5253SSM 3 trifluoroacetate

Potent furin inhibitor

Aug 2015
5020SF 1670

PTEN inhibitor

Aug 2015

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