All Products

Cat.No.

Product Name / Activity

Cathepsin inhibitor; interferes with autolysosomal digestion

K_V11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K⁺ current (I_Kr)

Group I/group II mGlu antagonist

Activator of Ca²⁺-activated Cl^- channel transmembrane protein 16A (TMEM16A)

Vitamin D receptor (VDR) agonist

Potent PARP-1 inhibitor

Activator of epithelial K_Ca channels

Aldose reductase inhibitor

Synthetic retinoid; induces differentiation of stem cells

α_Vβ₃ and glycoprotein IIb/IIIa (integrin α_IIbβ₃) inhibitor

Anti-ischemic and antioxidant

Selective PI-PLC inhibitor, also PAF receptor agonist

Chelating agent

Potent inhibitor of ER-associated protein degradation and translocation

α₂ antagonist and I₁, I₃ ligand

Ca²⁺ channel blocker (L- and T-type)

Inhibits formation of amyloid fibrils

Highly selective group II mGlu antagonist

Calcium chelating agent

Adenosine deaminase inhibitor

Potent inhibitor of Rac family GTPases

Inhibits TRPP3-mediated currents; also inhibits the Na⁺/H⁺ exchanger (NHE)

Selective iNOS inhibitor, acts arginine binding site

P-gp inhibitor

Potent tachykinin receptor ligand

Tachykinin receptor ligand

Orally active, selective 5-HT_1B/1D agonist

Non-competitive NR2B-selective NMDA antagonist

Selective inhibitor of CK2. Also inhibits glutathione S-transferase

Antitumor and intercalating agent; inhibits DNA topoisomerase II

5-HT₁ receptor agonist/partial agonist

Inhibitor of X-linked inhibitor of apoptosis (XIAP); cell-permeable and antitumor

Selective 5-HT_2A antagonist

Potent 5-HT₆ agonist

Potent, selective non-peptide AT₁ antagonist

Selective 5-HT₆ agonist

Naturally occurring anthraquinone; displays anti-inflammatory, antitumor and neuroprotective activity

Highly potent and selective OX₂ antagonist; brain penetrant

Highly selective A₁ agonist

Selection of 4 endogenous cannabinoids (Cat. Nos. 1339, 1568, 1411 and 1569)

Potent and selective μ agonist

Potent and selective μ agonist

Potent vasoconstrictor peptide

ET_A/ET_B agonist

Potent vasoconstrictor

Selective ET_B agonist

Potent antiestrogen; ERα ligand

Endogenous opioid agonist peptide

PDE3 inhibitor

Potent COMT inhibitor; blocks α-synuclein aggregation

Binds to β-subunit of F1-ATPase; anorexigenic peptide

Selective inhibitor of p38α and p38β₂

Very potent nicotinic agonist

Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II

Selective mineralocorticoid receptor antagonist

Endogenous IP receptor agonist

Microtubule stabilization agent; promotes tubulin polymerization

Potent and selective AT₁ receptor antagonist

Glycoprotein IIa/IIIb inhibitor; inhibits platelet aggregation

Selective Syk kinase inhibitor

Selective RARα antagonist

Potent ERβ agonist

Metabolite of vitamin D₂

Active metabolite of vitamin D₂

Mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase (NQO1)

Selective serotonin reuptake inhibitor (SSRI)

Endogenous estrogen receptor agonist

Endogenous ER agonist

Estrogen receptor agonist and OATP1B1 inhibitor

PDE4 inhibitor

Selective D₂/D₃ antagonist

Potentiator of GABA_A receptors; anxiolytic

Selective cyclooxygenase-2 (COX-2) inhibitor; NSAID

GABA mimetic and GABA modulatory agent

Carnitine palmitoyltransferase I (CPT1) inhibitor

Irreversible affinity label (μ selective)

Topoisomerase II inhibitor

Potent inhibitor of L-glutamate uptake into synaptic vesicles

Selective SIRT1 inhibitor

Selection of 5 EAAT inhibitors (Cat. Nos. 0183, 0298, 1223, 0111 and 0903)

Steroidal aromatase (CYP19) inhibitor

Potent GLP-1 receptor antagonist

Potent GLP-1 receptor agonist

Inhibits Golgi-ER traffic; blocks exocytosis